Harvard researchers report that supplementation in rats with a combination of uridine and EPA/DHA omega-3 fatty acids has antidepressant activity equivalent to that of commonly prescribed antidepressant medications, such as Prozac and other SSRIs.


(Carlezon WA, Mague SD, Parow AM, Stoll AL, Cohen BM, Renshaw PF (February 2005). "Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats". Biol Psychiatry 57 (4): 343-50. doi:10.1016/j.biopsych.2004.11.038)


Sources of uridine - (I hesitate! # ):

  • sugarcane extract [2]
  • tomatoes (0.5 to 1.0 g uridine per kilogram dry weight)[3]
  • brewer's yeast (3% uridine by dry weight)[4]
  • beer # [5]
  • broccoli[4]
  • organ meats (liver, pancreas, etc.)[4]


uridine definition noun


a nucleoside, CHNO, formed from uracil and ribose and found in RNA