Created: Wednesday, 01 February 2012 05:08
Conclusions - This study has indicated an association between epigenetic status and socio-economic status (SES). This relationship has direct implications for population health and is reflected in further associations between global DNA methylation content and emerging biomarkers of CVD.
Key words - DNA methylation, epigenetics, socio-economic status.
Abstract - http://ije.oxfordjournals.org/content/early/2012/01/08/ije.dyr215.short
Created: Friday, 27 January 2012 07:54
Introduction . . some genes from babies conceived by means of IVF show a gene expression pattern that is different from naturally conceived children (Katari et al., 2009). . . this mechanism could put children conceived by means of assisted reproduction treatment (ART) at a greater risk of diseases, such as diabetes and obesity, later in life.
Epigenetic deregulation already received increasing attention as a possible common cause of adverse ART outcomes, since the incidence of disorders that involve imprinted genes, especially the Beckwith–Wiedemann syndrome (BWS), is often reported to be increased in the offspring (Amor and Halliday, 2008, et al).
Conclusions . . ART can induce epigenetic variation that might be transmitted to the next generation.
Key words, assisted reproduction, epigenetics, human, genomic imprinting, transgenerational epigenetic inheritance.
More at - http://humupd.oxfordjournals.org/content/early/2012/01/19/humupd.dmr047.long